Observation of the Natural Course of Age-related Macular Degeneration

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age50-85
SponsorShanghai General Hospital, Shanghai Jiao Tong University School of Medicine

About this trial

This research will study natural course of dry AMD in Chinese population, screen fundus imaging indicators for patients with Chinese dry AMD, describe the clinical features of Chinese patients with dry AMD, and obtain a biological sample library of dry AMD mainly in China.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

50-85 yrs male or female AMD patients

Dry-AMD patients in either early, intermediate, or intermediate-to-late stage confirmed by fundus examinations.

Disqualifiers

Any eye with disease that would interfere with the retinal examinations

Research eye with CNV or high myopia

Surgeries that may interfere with AMD evaluation

Long-term uses of medications that are associated with retinal or neural toxicities.

Trial population

Dry AMD patients in Shanghai General Hospital

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

No trial groups listed

Trial outcomes

Primary outcomes

1

Visual acuity

A typical ETDRS chart that if frequently used for visual acuity testing

Time frame
60 months

Secondary outcomes

1

Drusen density and shape

Drusen Measurement on OCT or Fundus photography

Time frame
60 months
2

The rate of 5-year progression

The evaluation criteria for progression: progress to intermediate (only for patients with early phase AMD at baseline) or intermediate-to-late, or late stage AMD.

Time frame
60 months
3

GA growth rate

Time frame
60 months

Other outcomes

Sponsors and contacts

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This trial is not recruiting at the moment. You can still explore other options: