Greater advances are needed in two separate but related areas in healthcare: 1) the Clinical Decision Support Systems that complement the EHR use in support of routine patient care, population management and disease management; and 2) the use of the point-of-care observational data from the provider-patient encounter that support realworld medical research and healthcare quality measure assessment. Real-world evaluations of treatments of chronic diseases in the context of comorbid conditions and special populations (minorities, women, mentally ill, and those with addiction) are limited. The purpose of the OPERA database is to help address this unmet need in clinical research.
Patients who are treated in the practices who enroll and participate in the study
Patients whose treatment is documented in the practice's electronic health record system
Patients who opt out of OPERA
The patient population includes a diverse group of individuals treated in ambulatory practice with a focus on those living with chronic disease.
Cohort
Retrospective
Non-interventional (observational only)
Other interventionVirologic response to therapy
HIV-1 PCR laboratory value ("viral load") quantifies the amount of HIV-1 copies in plasma per mL. The baseline viral load is compared to viral load after 1 year of antiretroviral therapy.
