Observational Study on Patients With HIV/AIDS(OSPWH)
ConditionHIV Infections
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age14+
SponsorGuangzhou 8th People's Hospital
About this trial
To establish a follow-up cohort of antiretroviral therapy(ART) for patients with HIV/AIDS, to observe the ART efficacy and adverse reactions, complications in the process of ART, as well as mortality and causes of death, so as to provide basis for further improving ART efficacy and quality of life of the patients.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Patients has a history of diagnosis of HIV.
Receiving antiretroviral therapy.
Good treatment compliance.
Disqualifiers
Aged less than 14 years of old.
Trial population
Patients with HIV/AIDS who are willing to receive antiretroviral therapy.
Trial design
Design model
Cohort
Time perspective
Retrospective
Treatments tested in this trial
Not listed
Trial groups
No trial groups listed
Trial outcomes
Primary outcomes
1
The rate of virological suppression after antiretroviral therapy.
After ART, HIV RNA level in plasma were quantified every year. The rate of HIV-RNA\<400 copies/ml will be used to evaluate the efficacy of ART and the variation tendency of the rate of virological suppression will be described.
Time frame
Year 10Secondary outcomes
1
The CD4+T cell counts after ART.
The CD4+T cell count in plasma were detected every 3 months. The variation tendency of CD4+Tcell count will be described.
Time frame
Year 102
All-cause mortality among HIV/AIDS after ART.
Describe the all-cause mortality among HIV/AIDS after ART and analyze the trend.
Time frame
Year 103
The incidence of adverse reactions after ART.
In order to assess the adverse reactions after ART, the clinical symptoms were recorded, such as respiratory symptoms, digestive system symptoms, nervous system symptoms, and mental symptoms, etc. And cytological and biochemical indexes were detected such as blood routine, liver function, renal function, blood lipid, blood glucose, urine routine, etc. Calculate the incidence of adverse reactions after ART for 10 years.
Time frame
Year 10Sponsors and contacts
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Source ClinicalTrials.gov