About this trial
In this project, the investigators aim to assess changes of physiological parameters obtained non-invasively through PPG and accelerometry signals between before and during LTOT (long-term oxygen therapy) and investigate if those changes are different in patients with worsening frailty and/or improving quality of life.
For this, they will record optical (PPG) and accelerometry data via a datalogger on 40 patients undergoing LTOT and assess the PPG-derived physiological signals.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Age ≥ 18-year-old, and
Chronic respiratory disease including a) chronic obstructive pulmonary disease, b) interstitial lung disease, c) pulmonary hypertension, d) bronchiectasis, and
Prescribed new LTOT due to a chronic respiratory disease with resting and/or exertional hypoxemia, and
Able to speak/read/understand German or French, and
Disqualifiers
Pregnant or lactating women, or
Inability to follow the procedures/instructions of the study (e.g. due to language, psychological disorders, dementia, etc.), or
Patients having a subordination link to the investigators, or
Patients with isolated nocturnal oxygen therapy or LTOT prescription for a heart disease, sleep associated breathing disorder, neuromuscular disease or lung cancer, or
Trial population
Patients with a respiratory disease and newly prescribed LTOT
Trial design
Case-only
Prospective
Treatments tested in this trial
LTOT
Other interventionPatients with newly prescribed LTOT will be monitored for physiological changes
Treatment groups
Trial outcomes
Primary outcomes
Heart rate changes from before and during LTOT
Record heart rate (BPM) to compare before and during LTOT
Respiratory rate changes from before and during LTOT
Record respiratory rate (breaths per minute) to compare before and during LTOT
SpO2 changes from before and during LTOT
Record SpO2 (%) to compare before and during LTOT
Sponsors and contacts
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