Observing the Efficacy and Safety of Different Drugs Used in Real-world Familial Mediterranean Fever (FMF) Cases

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
AgeNot listed
SponsorTongji Hospital

About this trial

retrospective observe the efficacy and safety of different drugs used in familial Mediterranean fever (FMF) cases in real-world

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

None

Disqualifiers

Have a history of mental illness, or alcohol and drug dependence;

Pregnant, with severe infection, severe cardiac insufficiency, severe liver or kidney dysfunction;

Complicated with tumors, organ transplants, etc. which have significant impact on the immune system or require the use of immunosuppressants.

Trial population

familial Mediterranean fever (FMF) patients

Trial design

Design model

Cohort

Time perspective

Retrospective

Treatments tested in this trial

  • real word drugs

    Drug

    real word drugs

Treatment groups

No treatment groups listed

Trial outcomes

Primary outcomes

1

Clinical responses graded as Patient Global Assessment (PGA ) decrease

The treatment outcome was graded as PGA decrease:in-response, partial response, good response, or clinical remission corresponding to symptomatic improvement \<30%, 30% to 50%, 50% to 70%, or \>70%, respectively. PGA is a subjective measure where patients rate their overall disease activity or health status on a scale like a visual analog scale (VAS).

Time frame
From baseline,4, 8, 12, 24 and week 52

Secondary outcomes

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Tongji Hospital

Lead sponsor

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

Collaborator

Pfizer

Collaborator

Johns Hopkins University

Collaborator