About this trial
retrospective observe the efficacy and safety of different drugs used in familial Mediterranean fever (FMF) cases in real-world
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
None
Disqualifiers
Have a history of mental illness, or alcohol and drug dependence;
Pregnant, with severe infection, severe cardiac insufficiency, severe liver or kidney dysfunction;
Complicated with tumors, organ transplants, etc. which have significant impact on the immune system or require the use of immunosuppressants.
Trial population
familial Mediterranean fever (FMF) patients
Trial design
Cohort
Retrospective
Treatments tested in this trial
real word drugs
Drugreal word drugs
Treatment groups
Trial outcomes
Primary outcomes
Clinical responses graded as Patient Global Assessment (PGA ) decrease
The treatment outcome was graded as PGA decrease:in-response, partial response, good response, or clinical remission corresponding to symptomatic improvement \<30%, 30% to 50%, 50% to 70%, or \>70%, respectively. PGA is a subjective measure where patients rate their overall disease activity or health status on a scale like a visual analog scale (VAS).
Sponsors and contacts
Click on the lead sponsor to view all of their trials.
Tongji Hospital
Lead sponsor
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Collaborator
Pfizer
Collaborator
Johns Hopkins University
Collaborator