Obstructive Sleep Apnea Treatment From Acute to Chronic Phase of Stroke
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-80
SponsorHospital das Clínicas de Ribeirão Preto
About this trial
The study aims to evaluate whether early treatment of obstructive sleep apnea with continuous positive airway pressure in ischemic stroke patients has a favorable effect on functional recovery.
Eligibility criteria
Qualifiers
Supratentorial non-lacunar ischemic stroke, including anterior, middle, and posterior cerebral artery territories
Aged 18 to 80 years
Symptom onset or symptom recognition to admission < 12 hours
NIHSS score ≥ 4 and ≤ 20 at enrollment
Disqualifiers
Prior stroke
Previous diagnosis of OSA with current CPAP use or previously failed CPAP
Pre-stroke disability (mRS > 1)
Coma or stupor
Trial design
Treatments tested in this trial
- CPAP
Treatment groups
425 Participants
are divided into 5 treatment groupsSponsors and collaborators
Hospital das Clínicas de Ribeirão Preto
Lead sponsor
Fundação de Amparo à Pesquisa do Estado de São Paulo
Collaborator
ResMed Foundation
Collaborator
Source ClinicalTrials.gov