OCEAN Registry: Obesity and Clock for Elegant Aging Registry
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age20+
SponsorChang Gung Memorial Hospital
About this trial
This study aims to study the relationships between obesity, circadian rhythm, and aging. The investigators set up a prospective cohort registry for morbid obesity, obesity, and normal subjects with annual follow-up. The cohort aims to investigate the pathophysiological, molecular, genetic, and cellular aspects of the relationships between obesity, circadian deregulation, and impacts on aging. Clinical data, questionnaires, biological material, and molecular signatures will be collected and investigated.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Age ≥ 20 years old
Body mass index ≥ 24 kg/m2
For normal subjects, Body mass index < 24 kg/m2
Disqualifiers
No inform consent
Use of steroid medications
Severe systemic diseases or organ failure with estimated life expectancy of 6 months or less
Trial population
Subjects will be recruited from the general population including healthcare facility and non-health care settings. Healthcare facility includes university based hospital and primary care clinics. Non-health care settings include schools, subjects families, and employment agencies.
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
Not listed
Trial groups
2,000 Participants
are grouped into 3 trial groupsGroup A: Extreme obesity
Group B: Obesity
Group C: Normal subjects
Trial outcomes
Primary outcomes
1
Body weight
Time frame
10 yearsSecondary outcomes
1
Major Cardiovascular Adverse Events
Time frame
3, 6, 12, and 18 months. 2, 5, and 10 years2
Sleep quality as assessed by Pittsburgh Sleep Quality Index (PSQI) questionnaire
Time frame
3, 6, 12, and 18 months. 2, 5, and 10 years3
Personal chronotype (biological clock) as assessed by Munich Chronotype Questionnaire
Time frame
3, 6, 12, and 18 months. 2, 5, and 10 yearsSponsors and contacts
Click on the lead sponsor to view all of their trials.
Source ClinicalTrials.gov