OCT Eccentric Fixation and Amblyopia in Children

ConditionAmblyopia

Trial statusRecruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexAll

Age4-16

SponsorState University of New York College of Optometry

About this trial

The objectives of this proposal are to characterize the relationship between OCT eccentric fixation (OCT-EF), fixation eye movement (FEM), macular sensitivity in children with amblyopia.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

children with best-corrected visual acuity (BCVA) of 20/40 (equivalent to 0.3 logMAR) or worse in the amblyopic eye (ranging from 20/40 to 20/400), and interocular difference of BCVA was at least two logMAR lines,

ocular causes of amblyopia that were identified as refractive(i.e., anisometropic, strabismus, or strabismic-anisometropic.

Anisometropia included interocular difference of spherical equivalent >=1D or interocular difference of astigmatism cylinder magnitude >=1D;

strabismus included those with deviation >=10PD or good alignment after prior strabismus surgery;

Disqualifiers

born before 32 weeks gestational age;

neurologic, developmental, or systemic illnesses known to be associated with ocular pathologies;

congenital or acquired macular pathology.

Trial design

Design model

Parallel

Treatments tested in this trial

eye patch
Device
standard amblyopia treatment
After-image and MIT trainer
Device
Common clinical training for foveation

Treatment groups

30 Participants

are divided into 2 treatment groups

Group A: Patching groupExperimental treatment 1 intervention

Group B: foveation therapyExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

OCT eccentric fixation

eccentric fixation measured with OCT imaging.

Time frame

12 weeks

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

State University of New York College of Optometry

Lead sponsor

Source ClinicalTrials.gov

Apply now