Health TrialsbyHealthPanel

Off-set Analgesia Induced by Cold Temperature

ConditionPain
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-60
SponsorAalborg University

About this trial

In this study, it will be investigated if the phenomenon of offset analgesia, usually associated with painful heat stimulation, could also be induced using cold painful temperatures.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Healthy men and women

18-60 years

Speak and understand English

Disqualifiers

Pregnancy or lactation

Drug addiction defined as any use of cannabis, opioids, or other drugs

Previous or current history of neurological, immunological, musculoskeletal, cardiac disorder or psychiatric diagnoses that may affect the results (e.g., neuropathy, muscular pain in the upper extremities, anxiety, depression, schizophrenia, etc.)

Moles, wounds, scars, or tattoos in the area to be treated or tested

Trial design

Design model

Single group

Treatments tested in this trial

  • Heat off-set analgesia

    Other intervention

    The tests of off-set analgesia will be performed using a TSA2 (Medoc Ltd, Israel) thermal sensory testing device

  • Cold off-set analgesia

    Other intervention

    The tests of off-set analgesia will be performed using a TSA2 (Medoc Ltd, Israel) thermal sensory testing device.

Treatment groups

30 Participants
are divided into 1 treatment group
Group A: off-set analgesiaExperimental treatment 2 interventions

Trial outcomes

Primary outcomes

1

Measuring pain by computerized Visual Analog Scale Scoring

We will ask the subjects to rate the sensation of pain on a 100

Time frame
Immediately after the intervention

Secondary outcomes

1

Pain Catastrophizing Scale (PCS).

The PCS assesses negative and exaggerated coping concerning anticipated or experienced painful stimuli. Thirteen items have to be answered on a 5-point Likert-type scale ranging from 0 (Not at all) to 4 (all the time).

Time frame
Baseline
2

Learned Helplessness Scale (LHS)

The questionnaire consists of 20 items, and the participant's response to each item is rated on a 4-point Likert scale branging from strongly agree (1) to strongly disagree (4).

Time frame
Baseline
3

Depression, Anxiety, Stress Scale (DASS-21)

The questionnaire measures the magnitude of depression, anxiety, and stress. Each of these three subscales consists of 7 questions answered using a 0-3 Likert scale, with 0 meaning "it did not apply to me", and 3 meaning "it applied to me very much"

Time frame
Baseline
4

Reinforcement Sensitivity Theory - Personality Questionnaire (RST-PQ).

The RST-PQ contains in total 65 items must be answered on a Response scale: 4-point Likert (Strongly disagree → Strongly agree).

Time frame
Baseline

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Aalborg University

Lead sponsor

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: