Open Access Database of Standing Full Body Radiographs in Asymptomatic Volunteers
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age21-85
SponsorUniversity of Colorado, Denver
About this trial
A study of the skeletal structure and how the structure changes over time. The aim of the study is to evaluate the skeleton in 10 year increments to determine an understanding of the normal skeleton as a person ages. By using x-ray analysis, a new low dose x-ray system (EOS) can be used to evaluate the whole body to see changes in the bone structure over time. Subjects will be asked to undertake one x-ray analysis of their whole body skeletal structure. There will be 25 male and 25 female subjects per decade. The averaging of the measured skeletal parameters will provide information on changes over time generating a standardized expectation of general changes in skeletal structure as participants age.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Males and females age 21-85 without a history of spine surgery.
Disqualifiers
History of spine or neural axis surgery
History of cancer with or without metastatic disease
Connective tissue, rheumatologic (or other inflammatory arthropathies), or neurologic disorders
History of knee replacement surgery, as these may have contractures causing unexpected changes in alignment
Trial design
Design model
Single group
Treatments tested in this trial
EOS imaging
RadiationThe EOS imaging system will be utilized to obtain full-body radiographs in frontal and sagittal projections obtained in the upright standing position. Measurements will include a coronal plumb-line, sagittal vertebral axis (SVA), external auditory meatus plumb-line, cervical lordosis, thoracic kyphosis, lumbar lordosis, hip flexion/extension, knee flexion/extension, ankle flexion/extension, T1 tilt, T1 spino-pelvic instance, acetabular index, pelvic tilt (PT), pelvic incidence (PI), and sacral slope (SS).
Treatment groups
60 Participants
are divided into 1 treatment groupGroup A: asymptomatic EOS ImagingOther 1 intervention
Trial outcomes
Primary outcomes
1
Coronal plumb-line
Time frame
Through 1 EOS scan, 20 minutes2
Sagittal vertebral axis (SVA)
Time frame
Through 1 EOS scan, 20 minutes3
External auditory meatus plumb-line
Time frame
Through 1 EOS scan, 20 minutes4
Cervical lordosis
Time frame
Through 1 EOS scan, 20 minutesSponsors and contacts
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Source ClinicalTrials.gov