Health TrialsbyHealthPanel

Optimization of Cardiac Resynchronization Therapy by Non-Invasive Imaging of Cardiac Electrophysiology

ConditionHeart Failure
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorMedical University Innsbruck

About this trial

The principal aim is to analyze total left and right ventricular activation time in different CRT device programming algorithms (SyncAV) measured by non-invasive electrophysiology

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

patients after successful implantation of a CRT-D or CRT-P device in whom a cardiac magnetic resonance examination is possible and the device is equipped with the SyncAV® programming software

left bundle branch block before CRT implantation

PQ interval ≤ 250 ms before implantation

Disqualifiers

high-grade AV block

any contraindication concerning a safe CMR performance including claustrophobia

terminal heart failure (NYHA IV) or cardiac decompensation

life expectancy < 1 year

Trial design

Design model

Single group

Treatments tested in this trial

  • Device programming

    Device

    Non-invasive electrophysiology with 65 ECG leads will be performed in 16 different device programming

Treatment groups

25 Participants
are divided into 1 treatment group
Group A: Device programmingExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Optimal (shortest) activation time of the right and left ventricular in heart failure patients after CRT implantation

The activation time will be measured in 16 different device programming settings

Time frame
The measurements will be done at Day 1

Secondary outcomes

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Medical University Innsbruck

Lead sponsor

Source ClinicalTrials.gov
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