About this trial
Bronchiectasis is a chronic respiratory condition characterized by the abnormal and permanent dilation of the bronchi, leading to recurrent respiratory infections, chronic cough, and significant morbidity. The disease has gained increasing recognition due to its rising prevalence and the substantial burden it places on healthcare systems .
Recent studies have highlighted the importance of nutritional status in managing chronic respiratory diseases, including bronchiectasis. Malnutrition is prevalent among patients with bronchiectasis, particularly those experiencing frequent exacerbations. It has been shown that underweight patients have lower lung function and may face worse clinical outcomes compared to those with normal weight . Specifically, a study found that underweight individuals had a significantly lower forced expiratory volume in one second (FEV1) compared to their normal-weight counterparts, indicating a direct correlation between nutritional status and respiratory function .
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
*Age*: Adults aged 18 years and older.
Diagnosis*: Confirmed diagnosis of bronchiectasis, as established by clinical evaluation and imaging studies (e.g., chest CT scan).
Acute Exacerbation*: Patients presenting with acute exacerbation symptoms, such as increased sputum production, worsening dyspnea, or chest pain.
Nutritional Assessment*: Patients identified as malnourished or at risk of malnutrition based on the Subjective Global Assessment (SGA) or similar nutritional screening tools.
Disqualifiers
*Cognitive Impairment*: Patients with cognitive impairments that affect their ability to participate in the study or adhere to nutritional recommendations.
Current Enteral Feeding*: Patients receiving enteral nutrition or those with a feeding tube.
Trial population
Recruitment Patients will be recruited from inpatient wards. Informed consent will be obtained from all participants prior to enrollment. Nutritional Assessment * \*\*Baseline Assessment\*\*: * Nutritional status will be determined using the Subjective Global Assessment (SGA) and biochemical markers (e.g., serum albumin). * Dietary intake will be assessed using a 3-day food diary or 24-hour dietary recall method. * \*\*Nutritional Optimization\*\*: Patients identified as malnourished will receive a tailored nutritional intervention, which may include: * High-protein dietary recommendations. * Caloric supplementation through protein shakes or high-calorie snacks. * Micronutrient supplementation as need Data Collection Data will be collected at three time points: 1. \*\*Baseline\*\*: Upon admission. 2. \*\*During Hospitalization\*\*: After the implementation of nutritional interventions. 3. \*\*Follow-Up\*\*: Six months post-discharge, assessing long-term outcomes.
Trial design
Cohort
Prospective
Treatments tested in this trial
Not listed
Trial groups
Trial outcomes
Primary outcomes
Asses The Change In Quality of life
measured by the St. George's Respiratory Questionnaire (SGRQ).
Locations
Sponsors and contacts
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