About this trial
This study evaluates the feasibility of implementing a mobile extracorporeal membrane oxygenation (ECMO) team and optimizing patient transport logistics.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
out-of-hospital cardiac arrest
indication for ECPR
Disqualifiers
death at the scene of the accident
withdrawal of the informed consent
Trial population
Patients indicated for ECPR after out-of-hospital cardiac arrest, for whom transport of the patient to an ECMO centre or deployment of an ECMO team is logistically manage-able.
Trial design
Case-only
Prospective
Treatments tested in this trial
Extracorporeal cardiopulmonary resuscitation (ECPR)
Procedure/SurgeryExtracorporeal cardiopulmonary resuscitation (commonly known as ECPR) is a method of cardiopulmonary resuscitation (CPR) that passes the patient's blood through a machine in a process to oxygenate the blood supply.
Treatment groups
Trial outcomes
Primary outcomes
Neurological outcome after 30 days (CPC score)
Assessment of the neurological status of patients 30 days after the event using the Cerebral Performance Category (CPC) scale, which measures the extent of neurological impairment: * CPC 1 = good neurological condition * CPC 2 = mild impairment * CPC 3-5 = serious impairment, vegetative state or death The primary endpoint of the study is the proportion of patients with a favourable neurological outcome (CPC 1-2).
Secondary outcomes
Time from collapse to initiation of ECMO
Measuring the time (in minutes) from patient collapse to ECMO initiation. The aim is to analyse how this time affects neurological outcome.
Transport time to the ECMO centre
Measurement of the time (in minutes) from the arrival of the Emergency Medical Services (EMS) at the scene to the admission of the patient to the ECMO centre.
Arrival time for the mobile ECMO team to the scene
Time interval (in minutes) from activation of the mobile ECMO team to its arrival at the scene. The aim is to evaluate the effectiveness of the model and the potential time benefit of intervention in the field.
Sponsors and contacts
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University Hospital Ostrava
Lead sponsor
Emergency Medical Services, Moravian-Silesian Region
Collaborator