Health TrialsbyHealthPanel

Optimizing a Remote-based Physical Activity Intervention for Adults With Total Knee Replacement

ConditionKnee Replacement
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversity of South Carolina

About this trial

The purpose of this study is to identify which supplemental intervention components added to an online exercise program contribute to the greatest increases in physical activity (total MVPA and percent meeting guidelines \[≥150 min/week of MVPA\]) in adults with knee replacement at 6 and 12 months. Secondary outcomes will examine changes in pain and physical function.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

had a knee replacement (including primary, staged or independent bilateral, or revision) at least 12 months ago

have a computer, tablet, or smartphone with active internet access

self-report engaging in less than 60 minutes/week of moderate-intensity physical activity

be English-speaking and able to read consent and study materials written in English

Disqualifiers

any contraindications to physical activity (e.g., chest pain)

have a scheduled surgery within the next 12 months (e.g., hip or knee replacement)

have a mobility limiting comorbidity unrelated to knee replacement

live outside of the continental U.S

Trial design

Design model

Factorial

Treatments tested in this trial

  • Phone Coaching

    Behavioral

    Participants will receive 11 coaching calls with a health coach. Calls will occur weekly during the first month, twice/month during months 2-3, and once/month during months 4-6. Each call is expected to last 10-15 minutes.

  • Progress reports to providers

    Behavioral

    Progress reports on physical activity and program adherence will be sent to participants providers at 3 and 6 months.

  • 'Hear from Others' Videos

    Behavioral

    Participants will receive monthly 'Hear From Others' videos. The videos will include other adults with knee replacement discussing the challenges they have faced and strategies to overcome barriers to activity.

  • Individualized Feedback

    Behavioral

    Participants will receive individualized feedback from a coach via email. The feedback will specifically focus on participant responses to the 'Apply Your Knowledge' activities and will correspond with the video lessons. Feedback will be weekly during months 1-3 and monthly during months 4-6.

  • Online exercise program

    Behavioral

    MOST Energized! Online Exercise Program

Treatment groups

336 Participants
are divided into 16 treatment groups

16

Treatment groups

See each treatment group below.

Group A: Experimental condition 1Experimental treatment 5 interventions
Group B: Experimental condition 2Experimental treatment 4 interventions
Group C: Experimental condition 3Experimental treatment 4 interventions
Group D: Experimental condition 4Experimental treatment 3 interventions
Group E: Experimental condition 5Experimental treatment 4 interventions
Group F: Experimental condition 6Experimental treatment 3 interventions
Group G: Experimental condition 7Experimental treatment 3 interventions
Group H: Experimental condition 8Experimental treatment 2 interventions
Group I: Experimental condition 9Experimental treatment 4 interventions
Group J: Experimental condition 10Experimental treatment 3 interventions
Group K: Experimental condition 11Experimental treatment 3 interventions
Group L: Experimental condition 12Experimental treatment 2 interventions
Group M: Experimental condition 13Experimental treatment 3 interventions
Group N: Experimental condition 14Experimental treatment 2 interventions
Group O: Experimental condition 15Experimental treatment 2 interventions
Group P: Experimental condition 16Experimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Physical activity (min/week)

Change in Actigraph-assessed moderate-to-vigorous intensity physical activity

Time frame
Baseline to 6 months
2

Percentage meeting physical activity guidelines

Percentage of participants meeting physical activity guidelines (150 minutes/week)

Time frame
6 months
3

Physical activity (min/week)

Change in Actigraph-assessed moderate-to-vigorous intensity physical activity

Time frame
Baseline to 12 months
4

Percentage meeting physical activity guidelines

Percentage of participants meeting physical activity guidelines (150 minutes/week)

Time frame
12 months

Secondary outcomes

1

Pain intensity

Change in pain intensity using Patient-Reported Outcomes Measurement Information System (PROMIS)

Time frame
Baseline to 6 months
2

Physical Function

Change in physical function using the physical function/mobility Patient-Reported Outcomes Measurement Information System (PROMIS)

Time frame
Baseline to 6 months
3

Pain intensity

Change in pain intensity using Patient-Reported Outcomes Measurement Information System (PROMIS)

Time frame
Baseline to 12 months
4

Physical Function

Change in physical function using the physical function/mobility Patient-Reported Outcomes Measurement Information System (PROMIS)

Time frame
Baseline to 12 months

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

University of South Carolina

Lead sponsor

National Institute on Aging (NIA)

Collaborator

Source ClinicalTrials.gov
Apply now