Optimizing Long-term Survival in Organ Transplantation: From Physiopathology to Optimized Patient Management

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversity Hospital, Limoges

About this trial

Increased indications for transplantation continue to worsen the shortage of organs and need the extension of graft sampling criteria and the search for new potential sources of organs. Despite undeniable success in the short term, due to major advances in surgery, medicine and research, transplant recipients continue to face the risk of chronic rejection and long-term complications.

The University Hospital Federation "FHU SUPORT" was created to optimize the chances of success of the organ transplant and improve the quality of life of the transplanted patient. FHU SUPORT 's ambition is based on a translational strategy that presents two priority areas:

Axis 1: Optimization, evaluation, conditioning of the donor, graft, recipient Axis 2: Personalized follow-up of the transplanted patient in the short and long term Identifying factors for long-term graft and patient survival through translational research from a common cohort and biological collection will predict transplant rejection, prolong graft function, or improve the patient's care.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Male or female over 18 (no age limit)

affiliated to a social security organization

Recipient (s) of a kidney, liver or heart transplant

followed by at least one of the FHU SUPORT centers (Tours, Poitiers, Limoges, Rennes)

Disqualifiers

Patient unable to understand the information given by the investigator

People under the protection of justice

Trial design

Design model

Single group

Treatments tested in this trial

  • blood and urine samples

    Other intervention

    various blood and urine samples will be collected from the recipient at D0, D7, D14, M1, M3, M6 and M12 and intraoperative bile collection

Treatment groups

430 Participants
are divided into 1 treatment group
Group A: blood, bile and urine samplesExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Survival of the graft

Time frame
12 months

Secondary outcomes

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

University Hospital, Limoges

Lead sponsor

University Hospital Federation FHU SUPORT

Collaborator