Health TrialsbyHealthPanel

Optimizing Strength Training in Older Adults

ConditionAging
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age65+
SponsorQueens College, The City University of New York

About this trial

The objective of the current study is to determine whether lifting lighter loads close to failure improves strength training adaptations and function in older adults. The main questions it aims to answer are:

1. The effect of light loads on physical function 2. The effect of light loads on muscle mass, power, and strength

Researchers will compare a light-load, high-repetition program to a standard strength training program. Participants will perform supervised strength training twice per week for 20 weeks.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Males and females aged 65 years and above

Inactive lifestyle (< 150 min per week of moderate intensity physical activity) and not regularly participating in a structured strength training program

Planning to reside in the area for the duration of the study

Disqualifiers

Severe cardiac disease, including Class III or IV congestive heart failure, clinically significant aortic stenosis, history of cardiac arrest, use of a cardiac defibrillator, or uncontrolled angina

Lung disease requiring either oral or injected steroids, or the use of supplemental oxygen

Short, portable mental status questionnaire with 3 or more errors

Severe arthritis (either osteoarthritis or rheumatoid arthritis)

Trial design

Design model

Parallel

Treatments tested in this trial

  • Strength training

    Behavioral

    This intervention involves strength training with lighter loads and higher repetitions.

  • Strength training

    Behavioral

    This intervention involves conventional strength training with higher loads and moderate repetitions.

Treatment groups

68 Participants
are divided into 2 treatment groups
Group A: Light Load, High Repetition (LLHR)Experimental treatment 1 intervention
Group B: Strength Training (ST)Active comparator 1 intervention

Trial outcomes

Primary outcomes

1

6-minute walk test

Change in the total distance walked in 6 minutes. The 6-minute walk test is an objective, well-validated, and clinically meaningful measure of physical function in older adults.

Time frame
Baseline and week 21

Secondary outcomes

1

Lower body maximal muscle strength

Change in lower body maximum muscle strength will be assessed using a one-repetition maximum (1RM) test on a leg press machine.

Time frame
Baseline and week 21.
2

Lower body muscle power

Lower body muscle peak power (W) will be assessed using a pneumatic leg press machine.

Time frame
Baseline and week 21
3

Lean body mass (LBM)

Change in total lean body mass (kg) will be assessed using a dual-energy X-ray absorptiometry (DXA) scan

Time frame
Baseline and week 21
4

Self-reported physical function

Self-reported physical function will be assessed using the Patient-Reported Outcomes Measurement Information System (PROMIS) physical function questionnaire. PROMIS measures are scored on the T-score metric. High scores mean more of the concept being measured.

Time frame
Baseline and week 21

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Queens College, The City University of New York

Lead sponsor

National Institute on Aging (NIA)

Collaborator

Source ClinicalTrials.gov
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