When the heart stops pumping during cardiac arrest, cardiopulmonary resuscitation (CPR) is used to continue pushing blood and providing oxygen to vital organs. CPR involves a combination of chest compressions (to push the blood) and ventilations (to provide oxygen and gas exchange). There is a lot of research that has helped to optimize the provision of chest compressions, however there is considerably less research available to guide ventilations. The current guideline recommendations are based on limited data, and no data that is specific to cardiac arrest patients. There is a recognized need for research to better guide ventilation during CPR. This research will help to better define appropriate ventilation targets for cardiac arrest patients.
Adult (>=18 years of age)
presumed cardiac etiology
treated by paramedics
Ventilation monitor utilized
Do Not Resuscitate (DNR) order
No use of ventilation monitor
Traumatic cardiac arrest
Pregnant patients
Crossover
Low Volume Ventilation
Other interventionPatients in cardiac arrest will be ventilated with a volume of 350ml (+/- 50 ml)
High Volume Ventilation
Other intervention600ml (+/-50ml)
Return of Spontaneous Circulation
At any time in the prehospital setting as documented by paramedics
Survival to Hospital Discharge
Survival at hospital discharge
Survival to Hospital Admission
Survival to hospital admission obtained through administrative datasets
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Sunnybrook Health Sciences Centre
Lead sponsor
Zoll Medical Corporation
Collaborator
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