Oral Cancer Screening for Early Detection of Premalignant Disorders (PMOD)
ConditionMouth Neoplasms
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorDalarna County Council, Sweden
About this trial
Cancer is a complex disease; its different causes and types have a strong impact on patient treatment and prognosis. To improve understanding of the disease, its causes and progression, the investigators will develop a simple, cost-effective system for continuous control of mucosal lesions with non-invasive brush biopsy that can be managed in primary dental care, as an alternative to tissue biopsy in order to reduce the number of oral cavity cancers.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
None
Disqualifiers
People who cannot read and understand information in Swedish.
Ongoing chemotherapy and/or radiotherapy.
Trial design
Design model
Parallel
Treatments tested in this trial
Brush sampling
Procedure/SurgeryBrush sampling instead of surgical biopsy for control of reaccurance
Treatment groups
200 Participants
are divided into 2 treatment groupsGroup A: Brush biopsyExperimental treatment 1 intervention
Group B: Care as usualActive comparator 1 intervention
Trial outcomes
Primary outcomes
1
Numbers of cancers diagnosed by brush sampling
Time frame
5 yearsSponsors and contacts
Click on the lead sponsor to view all of their trials.
Dalarna County Council, Sweden
Lead sponsor
Uppsala University
Collaborator
Source ClinicalTrials.gov