Pregnant women are susceptible to develop periodontitis, but these oral health changes related to pregnancy are often neglected. Periodontitis is accompanied by a low-grade systemic inflammation and can be harmful to the general health of the woman, contribute to pre-term birth and adversely influence the future health and metabolism of the offspring. Despite this, studies indicate that 40% of Danish women in childbearing age do not visit a dentist regularly. The PROBE controlled intervention study will investigate the beneficial effect of treatment of periodontal disease during pregnancy on fetal growth, preterm delivery and birth weight.
Pregnant women who are planned to give birth at either Holbaek or Nykoebing Falster hospital
Pregnant women diagnosed with periodontitis (stage I-III) by the study dentist
Pregnant women without peridontitis
Pregnant women with less than 20 healthy teeths
Pregnant women with peridontitis and currently receiving treatment for peridontitis
Pregnant women with peridontitis stage IV
Parallel
Periodontal treatment
Other interventionPeriodontal treatment
Prevalence of preterm birth
Defined as any birth before 37 completed weeks of gestation
Prevalence of low birthweight
Defined as a birth weight of less than 2500 gram
Increased risk markers for preeclampsia
Defined as hypertension and proteinuria
Prevalence of gestational diabetes
Defined as glucose intolerance
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