The goal of this observational study is to explore whether oral health and saliva viscosity and composition in Oculopharyngeal Muscular Dystrophy (OPMD) is different from control subjects.
The main questions it aims to answer are:
Do swallowing disturbances in OPMD adversely affect oral health? Is saliva thickness (viscosity) is increased in OPMD? Does saliva in OPMD contains biochemical markers of the disease?
Patients with OPMD and their spouses or household members
• Pregnancy or presence of any disease that may affect a composition of saliva
The Patients group: consisted OPMD patients enrolled in IsrOPMD registry at the multidisciplinary OPMD service at the Sheba Medical Center. The Control group: patients' spouse or household member without OPMD.
Family-based
Cross-sectional
Not listed
Saliva Viscosity
Viscosity of unstimulated whole saliva
Oral health indices
DMFT, presence of tongue coating, clinical appearance of saliva and saliva-related complains
Concentration of Metabolites in saliva
Differences in concentration of metabolites in unstimulated whole saliva of patients and control groups.
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