The purpose of this retrospective study was to characterize the changes in organ dysfunction among patients with acute necrotizing pancreatitis complicated by sepsis who underwent open necrosectomy.
Patients 18 years or older
Diagnosis of Acute pancreatitis according to the revised Atlanta classification, requires two of thefollowing three criteria: (A) typical abdominal pain, (B) an increase in serum amylase or lipaselevels higher than three times the upper limit of normality, and (C) signs of AP in imaging3)Patients with confirmed or suspected infected pancreatic or peripancreatic necrosis werescheduled for open necrosectomy
Meet Sepsis-3 criteria
None
This retrospective cohort included patients with acute necrotizing pancreatitis complicated by sepsis who underwent open necrosectomy
Cohort
Retrospective
Necrotizing Pancreatitis patients' organdysfunction progression
Other interventionStudy the dynamic nature of organ dysfunction
Measure organ dysfunction change after open necrosectomy with respect to time
Organ dysfunction was assessed retrospectively using the Sequential Organ Failure Assessment (SOFA) score, which ranges from 0 (normal) to 4 (most abnormal) for each organ, with higher scores indicating more severe dysfunction.
Incidence of ICU mortality
Incidence of hospital mortality
Incidence of 28-day mortality
Incidence of one year mortality
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