ORI MONITORING IN LOW AND NORMAL FLOW ANESTHESIA APPLICATIONS

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-75
SponsorBaşakşehir Çam & Sakura City Hospital

About this trial

Oxygen administration is essential in the perioperative period to prevent hypoxia; however, excessive oxygen may cause hyperoxia and related complications. While pulse oximetry is effective in detecting hypoxemia, it is insufficient for identifying hyperoxia when SpO₂ exceeds 97%, often necessitating invasive arterial blood gas analysis. The Oxygen Reserve Index (ORI) is a noninvasive, real-time monitoring parameter reflecting moderate hyperoxic ranges (PaO₂ 100-200 mmHg) and provides early warning of oxygenation changes before SpO₂ alterations occur. Combined use of ORI and pulse oximetry may enable optimal oxygen titration and prevention of both hypoxemia and hyperoxemia.

Laparoscopic nephrectomy is widely performed due to its clinical advantages. In our practice, low and normal fresh gas flow anesthesia are commonly used. Low-flow anesthesia offers benefits such as preservation of heat and humidity, reduced cost, and improved airway physiology. This study aims to determine optimal oxygenation levels during laparoscopic nephrectomy under low and normal fresh gas flow conditions using ORI monitoring.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Ages 18-75

ASA I,II

elective surgery laparoscopic nephrectomy

Disqualifiers

ASA III,IV,V

BMI > 35

Those with serious respiratory disease

Medications that cause peripheral circulation disorders

Trial population

Ages 18-75, ASA I,II, elective surgery laparoscopic nephrectomy

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

48 Participants
are grouped into 2 trial groups
Group A: low-flow anesthesia
Group B: normal flow anesthesia

Trial outcomes

Primary outcomes

1

Early detection of hypoxia and hyperoxia in laparoscopic nephrectomy cases with low and normal flow anesthesia using ORI monitoring.

Time frame
Perioperative period(approximately 3-6 hours

Secondary outcomes

1

The effect of lateral decubitus position on oxygenation in laparoscopic nephrectomies

Time frame
Perioperative period(approximately 3-6 hours)

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

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