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Oropharyngeal Vs Intravenous Lidocaine Effects on Optic Nerve Sheath Diameter After Intubation

ConditionsEndotracheal Intubation During SurgeryOptic Nerve Sheath Diameter
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-65
SponsorAnkara City Hospital Bilkent

About this trial

This study aims to evaluate the effects of pre-intubation oropharyngeal topical lidocaine on optic nerve sheath diameter (ONSD) post-endotracheal intubation. The study will measure the ONSD using ultrasonography before intubation, and at 1, 5, and 10 minutes post-intubation. The results will be compared between patients receiving %10 lidocaine topically and %2 intravenous lidocaine.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

ASA class I or II

Age 18-65 years

BMI 18-30

No history or expected difficult intubation

Disqualifiers

ASA class III and above

Obesity (BMI > 30)

Difficult intubation history or risk

Glaucoma or other ophthalmic pathology

Trial design

Design model

Parallel

Treatments tested in this trial

  • Optic nerve sheath diameter measurement 0

    Diagnostic test

    optic nerve sheath diameter (ONSD) measured via ultrasonography before intubation

  • optic nerve sheath diameter measurement 1

    Diagnostic test

    optic nerve sheath diameter measurement 1 via ultrasonography after intubation 1st minute

  • optic nerve sheath diameter measurement 2

    Diagnostic test

    optic nerve sheath diameter measurement via ultrasonography after intubation 5th minute

  • optic nerve sheath diameter measurement 3

    Diagnostic test

    optic nerve sheath diameter measurement via ultrasonography after intubation 10th minute

  • Pre-intubation oropharyngeal topical %10 lidocaine

    Procedure/Surgery

    Pre-intubation oropharyngeal topical %10 lidocaine

  • Pre-intubation intravenous %2 lidocaine

    Procedure/Surgery

    Pre-intubation intravenous %2 lidocaine

Treatment groups

190 Participants
are divided into 2 treatment groups
Group A: Group A: Pre-intubation oropharyngeal topical %10 lidocaineExperimental treatment 5 interventions
Group B: Group B: Pre-intubation intravenous %2 lidocaineExperimental treatment 5 interventions

Trial outcomes

Primary outcomes

1

Optic nerve sheath diameter 0

optic nerve sheath diameter (ONSD) measured via ultrasonography before intubation

Time frame
Before intubation
2

Optic nerve sheath diameter 1

optic nerve sheath diameter (ONSD) measured via ultrasonography 1 minute after intubation

Time frame
1 minute after intubation
3

Optic nerve sheath diameter 2

Optic nerve sheath diameter (ONSD) measured via ultrasonography 5 minutes after intubation

Time frame
5 minutes after intubation
4

0ptic nerve sheath diameter 3

0ptic nerve sheath diameter (ONSD) measured via ultrasonography 10th minutes after intubation

Time frame
10th minutes after intubation

Secondary outcomes

1

Postoperative sore throat

Postoperative sore throat is evaluated with Visual Analog scale

Time frame
1 hour after recovery room admission

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Ankara City Hospital Bilkent

Lead sponsor

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: