Health TrialsbyHealthPanel

Outcome of Hyaluronic Acid Gel Versus Petroleum Jelly in Treatment of Epistaxis

ConditionEpistaxis
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
AgeNot listed
SponsorAssiut University

About this trial

The aim of this study is to compare the efficacy of Hyaluronic Acid Gel with Petroleum Jelly in treatment of epistaxis.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Patients with anterior localized idiopathic epistaxis

Disqualifiers

Patients wit secondary epistaxis (posttraumatic, postoperative, tumoral).

During pregnancy.

Patients wit major systemic disease (Blood Disease, Hypertension).

Trial design

Design model

Parallel

Treatments tested in this trial

  • Hyaluronic Acid Gel

    Drug

    "Topical hyaluronic acid gel will be applied to the nasal mucosa of participants for the treatment of epistaxis. The gel will be administered according to the study protocol and frequency, and outcomes will be assessed throughout the study period."

  • Petroleum jelly

    Drug

    "Topical petroleum jelly will be applied to the nasal mucosa of participants for the treatment of epistaxis. The application will follow the study protocol, and outcomes will be monitored and recorded over the study period."

Treatment groups

50 Participants
are divided into 2 treatment groups
Group A: Hyaluronic Acid GelExperimental treatment 1 intervention
Group B: Petroleum JellyExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

To compare the recurrence rate of epistaxis between the two groups

"Proportion of participants whose epistaxis stops completely within 7 days of treatment application."

Time frame
14 days

Secondary outcomes

1

To assess time to symptom resolution

"Time in minutes or hours from first application to complete cessation of nasal bleeding."

Time frame
Within 24 hours
2

To evaluate mucosal healing (endoscopic findings)

"Assessment of nasal mucosa healing using endoscopic examination after application of hyaluronic acid gel or petroleum jelly, scored according to a standardized mucosal healing scale."

Time frame
7-14 days
3

To assess patient comfort and compliance

"Measured using a standardized questionnaire or visual analog scale during the treatment period."

Time frame
7 days
4

To record adverse effects

"Incidence of local irritation, allergic reactions, or other side effects related to the topical intervention."

Time frame
14 days

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Assiut University

Lead sponsor

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: