Ovarian Reserve in Intensive Care Patients

ConditionAnti-Mullerian Hormone Deficiency

Trial statusNot yet recruiting

Trial phaseNot listed

Trial typeObservational

Biological sexFemale

Age18-35

SponsorHaseki Training and Research Hospital

About this trial

Gastrointestinal, pulmonary, nephrological, cardiac, neurologic and psychological effects in critically ill patients followed in the intensive care unit have been shown in the literature. However, the effects on ovarian reserve in these patients have not been sufficiently investigated and studies investigating this issue are limited in the literature. The synthesis, release frequency and amplitude of reproductive hormones change under stress. In addition, changes in ovarian homeostasis affect ovarian reserve. The aim of this study was to evaluate ovarian reserve in critically ill patients followed up in the intensive care unit.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

18-35 years of age

Female patients followed in the intensive care unit for more than 24 hours for internal or surgical reasons,

Women whose ovarian reserve is being evaluated,

Disqualifiers

Previous ovarian surgery, endometriosis, endometrioma,

History of chemotherapy, radiotherapy,

Ovarian cyst, malignancy and other ovarian pathologies,

Women with single ovary,

Trial population

a group of healthy women without any disease and a group of patients hospitalized in intensive care unit.

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

Glaskow coma scala, The Acute Physiology and Chronic Health Evaluation System- APACHE, Injury Severity Score- ISS)
Behavioral
The uterus, endometrium and ovarian characteristics, endometrial thickness, ovarian follicle number and ovarian volume parameters, hormone panel (FSH, LH, E2, AMH), cortisol, prolactin and thyroid function tests routinely examined for ovarian reserve will be evaluated in the study.

Treatment groups

75 Participants

are divided into 3 treatment groups

Group A: internal intensive care1 intervention

Group B: surgical intensive care1 intervention

Group C: Outpatient clinic patients1 intervention

Trial outcomes

Primary outcomes

ovarian follicle count

Ovarian reserve will be checked with ultrasound

Time frame

24 hour

Locations

This trial has no locations.

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Haseki Training and Research Hospital

Lead sponsor

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: