Oxytocin in Postmenopausal Women
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexFemale
Age18+
SponsorUniversity Hospital, Basel, Switzerland
About this trial
The aim of the present study is to assess whether cumulative endogenous neurophysin I secretion over one month differs between premenopausal and postmenopausal women. Using repeated measurements of neurophysin-I (NP-I, equimolar surrogate marker of oxytocin) across defined physiological time points, this study investigates oxytocin system regulation under cyclic and non-cyclic hormonal conditions.
The primary hypothesis is that cumulative NP-I release, expressed as the area under the curve (AUC) is lower in the postmenopausal group compared to the premenopausal group.
Eligibility criteria
Qualifiers
Female sex at birth
Age ≥18 years
Disqualifiers
Pregnancy or breastfeeding
Use of hormonal contraception or hormone replacement therapy within the last 3 months
Known endocrine disorders affecting the hypothalamic-pituitary-gonadal axis
Use of medications
Trial design
Treatments tested in this trial
- Repeated assessments
Treatment groups
30 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov