Parkinson's Families Project
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age16+
SponsorUniversity College, London
About this trial
One person in every 500 has Parkinson's and around 127,000 people are living with the condition in the UK. The aim of the study is to identify new genes that predispose or cause Parkinson's Disease or Parkinsonism. There is a pressing need to study the genetic makeup of family members both with and without Parkinson's. As families share a common genetic background, it is easier to find new Parkinson's genes by studying the genetic makeup of people with Parkinson's alongside other members of their families. We are particularly interested in studying the genetic makeup of two groups of people:
1. those who developed Parkinson's before the age of 45; and 2. those who have a family history of other relatives affected by Parkinson's.
By identifying genetic factors that cause Parkinson's, we hope to understand more about the condition. Doing so will lead to the development of better diagnosis, improved disease models, and we hope in time, to the development of better treatment.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
None
Disqualifiers
None
Trial population
Participants will be recruited from specialist secondary care clinics at collaborating centres in the United Kingdom. Participants can also be recruited from the community, through advertisements in patient newsletters and websites.
Trial design
Design model
Family-based
Time perspective
Cross-sectional
Treatments tested in this trial
Not listed
Trial groups
2,000 Participants
are grouped into 3 trial groupsGroup A: Index case
Group B: Affected relatives
Group C: Unaffected relatives
Trial outcomes
Primary outcomes
1
Number of participants who are clinically affected by Parkinson's disease or Parkinsonism, in relation to genetic factors.
Time frame
Through study completion, approximately 10 yearsSponsors and contacts
Click on the lead sponsor to view all of their trials.
University College, London
Lead sponsor
Parkinson's UK
Collaborator
Royal Free Hospital NHS Foundation Trust
Collaborator
Source ClinicalTrials.gov