Parkinson's Foundation PD GENEration Genetic Registry
ConditionParkinson's Disease
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorParkinson's Foundation
About this trial
Development of a central repository for PD-related genomic data for future research.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Study Population 1: PWP (open for recruitment)
Meet Movement Disorder Society (MDS) Clinical Diagnostic Criteria for Parkinson's Disease: probable diagnosis.
Willingness to undergo genetic testing, and choose to be informed of genetic testing results for GBA, LRRK2 and 5 additional PD related genes (SNCA, VPS35, PRKN, PINK-1, PARK7).
Capacity to give full informed consent in writing or electronically, and have read and signed the informed consent forms (ICFs) based on site clinician's determination.
Disqualifiers
Diagnosis of an atypical parkinsonian disorder (i.e., multiple system atrophy, progressive supranuclear palsy, dementia with Lewy bodies, corticobasal syndrome), including that due to medications, metabolic disorders, encephalitis, cerebrovascular disease, or normal pressure hydrocephalus.
Individuals who have received a blood transfusion within the past 3 months.
Individuals who have active hematologic malignancies such as lymphoma or leukemia.
Individuals who have had a bone marrow transplant within the past 5 years.
Trial population
Any person with probable diagnosis of Parkinson's disease according to the Movement Disorders Society criteria.
Trial design
Design model
Case-only
Time perspective
Cross-sectional
Treatments tested in this trial
Lab Assay for seven genetic variants for Parkinson's Disease
DeviceCounseling provided to participant by site clinician/physician/genetic counselor.
Treatment groups
No treatment groups listed
Trial outcomes
Primary outcomes
1
Prevalence of Parkinson's related genetic mutations in an convenience cohort
Identify people with Parkinson's who have genetic mutations to advance basic science and clinical research.
Time frame
6 months2
Educating people with Parkinson's of their genetic mutation status through genetic testing and counseling
People who are informed of their genetic status may be empowered to learn more about their disease and participant in clinical research.
Time frame
6 monthsSponsors and contacts
Click on the lead sponsor to view all of their trials.
Parkinson's Foundation
Lead sponsor
Indiana University
Collaborator
Fulgent Genetics
Collaborator
The Parkinson Study Group
Collaborator
Source ClinicalTrials.gov