Partnering to Enhance Emerging Adults' Response to Programs
ConditionAlcohol Use, Unspecified
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-24
SponsorUConn Health
About this trial
The goal of this clinical trial (CT) is to learn more about emerging adults' and their peers. Here, we will see how co-participating with a peer in health program might impact brain and behavior change over time.
Eligible youth will be invited to come in for a "Participation Day," during which they and a peer will independently complete questionnaires. With a peer, they will then complete a short health program, and undergo a brain scan (fMRI) while completing activities. Our study team will reach out to each participant individually again 3, 6, and 12 months later to learn about health behaviors over time.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
within the specified age range
agree to be contacted for the 3, 6, and 12 month follow ups
provide fully informed consent
Disqualifiers
left-handed
evidence of brain injury/illness and/or neurological, neurodevelopmental disorder including psychosis and related medications (e.g., antipsychotics; neuroleptics)
loss of consciousness ≥ 2 minutes
other fMRI contraindications (e.g., unremovable metal on/in body, pregnant)
Trial design
Design model
Single group
Treatments tested in this trial
Motivational Interviewing (MI)
BehavioralMotivational interviewing with peer dyads starts with an open-ended exploration of the dyad's hazardous drinking behavior via personal stories about alcohol use. It includes a values clarification task and age-matched norms along with personalized feedback regarding the dyad's alcohol use. The goal of the session is to engage the dyad in a thoughtful conversation about drinking and the implications it may have on their lives, with an eye to bolstering and supporting inherent drive for behavior change.
Treatment groups
248 Participants
are divided into 1 treatment groupGroup A: Motivational Interviewing (MI)Experimental treatment 1 intervention
Trial outcomes
Primary outcomes
1
Blood oxygen level dependent (BOLD) response synchrony
Mean BOLD time series will be obtained for each region of interest (ROI) during peer-directed change talk trials and temporally aligned across dyad participants. Inter-brain synchrony will be quantified using z-transformed GLM β-weights within ROIs between the BOLD time series of dyad members.
Time frame
Baseline2
BOLD response synchrony association with behavior change (past month alcohol use days)
Pearson correlation coefficients (r) of Primary Outcome #1 (ROI z-scores representing BOLD response synchrony) with individual Timeline Followback (TLFB) past month drinking days at 12 month follow up.
Time frame
12 MonthsSecondary outcomes
1
BOLD response synchrony association with behavior change (past month alcohol use days)
Pearson correlation coefficients (r) of Primary Outcome #1 (ROI z-scores representing BOLD response synchrony) with individual Timeline Followback (TLFB) past month drinking days at 3 month follow up.
Time frame
3 Months2
BOLD response synchrony association with behavior change (past month alcohol use days)
Pearson correlation coefficients (r) of Primary Outcome #1 (ROI z-scores representing BOLD response synchrony) with individual Timeline Followback (TLFB) past month drinking days at 6 month follow up.
Time frame
6 MonthsSponsors and contacts
Click on the lead sponsor to view all of their trials.
UConn Health
Lead sponsor
University of Texas
Collaborator
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Collaborator
Source ClinicalTrials.gov