Pathogenesis of Pediatric Nonalcoholic Fatty Liver Disease (NAFLD)
ConditionNAFLD
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age12-18
SponsorYale University
About this trial
The main aim of the study is to discover the mechanisms underlying the pathophysiology of NAFLD in obese youth.
Eligibility criteria
Qualifiers
Good general health, taking no medication on a chronic basis;
age 12 to 18 years, in puberty (girls and boys: Tanner stage II-V);
BMI >85th for obese cohort;
Disqualifiers
Baseline creatinine >1.0 mg; pregnancy;
the presence of endocrinopathies (e.g. Cushing syndrome);
cardiac or pulmonary or other significant chronic illness;
adolescents with a psychiatric disorder or with substance abuse;
Trial design
Treatments tested in this trial
- Usual diet and physical activity
Treatment groups
No treatment groups listed
Sponsors and collaborators
Yale University
Lead sponsor
National Institute on Minority Health and Health Disparities (NIMHD)
Collaborator
Source ClinicalTrials.gov