Health TrialsbyHealthPanel

Pathophysiological Basis of Hidradenitis Suppurativa

ConditionHidradenitis Suppurativa
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
AgeNot listed
SponsorClinical Hospital Center Rijeka

About this trial

HS is a chronic inflammatory disease manifested by recurrent inflammatory nodules, abscesses and tunnels under the skin. This disease is characterized by an inflammatory process that takes place in hair follicles, sebaceous glands and surrounding tissue. Because of its frequent recurrence and chronicity, it represents a major public health problem and there is a need for better diagnosis and new and more effective drugs. This research can be a part of realizing the stated needs.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Hidradenitis Suppurativa

Disqualifiers

patients with no HS

patients who do not want to be in the clinical trial

Trial population

Patiens with HS that are controlled in the region of CHC Rijeka

Trial design

Design model

Case-only

Time perspective

Prospective

Treatments tested in this trial

  • excision

    Procedure/Surgery

    excision of the affected area

Treatment groups

50 Participants
are divided into 1 treatment group
Group A: surgical procedure1 intervention

Trial outcomes

Primary outcomes

1

The pathohistological changes

The pathohistological changes in skin and subcutaneous tissues of patients with HS Hurley stage I and II and healthy patients (control group) will be assessed and compared them with each other.

Time frame
24 months

Secondary outcomes

1

The expression of cytokines

The expression of IL-1β, TNF-α, IL-8 and IL-10 by immunohistochemical method in skin and subcutaneous tissue of patients with HS Hurley stage II and III and healthy patients (control group) will be assessed and compared with each other

Time frame
24 months
2

The correlation of the clinical Hurley classification and pathohistological changes

The clinical Hurley classification and pathohistological changes in the removed skin are meant to be correlated

Time frame
12 months

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Clinical Hospital Center Rijeka

Lead sponsor

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: