About this trial
The goal of this observational qualitative study is to learn about the experiences and perspectives of patients with neurogenic lower urinary tract dysfunction (NLUTD) and their caregivers regarding different types of intravesical instillations used for urinary health. The study aims to understand the perceived benefits, challenges, and opportunities related to Lactobacillus-only, gentamicin-only, and combined gentamicin-Lactobacillus instillations. The main question this study seeks to answer is:
1\. Determine patient and caregivers' preferences, and overall experiences regarding intravesical therapeutics for urinary symptoms and UTI
Researchers will compare responses from four groups: participants who have used Lactobacillus-only instillations, gentamicin-only instillations, combined gentamicin-Lactobacillus instillations, and caregivers who have experience supporting instillations.
Participants will take part in a one-hour semi-structured interview and may be contacted for brief follow-up discussions to clarify findings. Interviews will be audio-recorded, transcribed, and analyzed using qualitative data software to identify themes related to treatment preferences and acceptability.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Age 18+
Diagnosis of NLUTD
Chronic catheter usage (minimum 6 months), either intermittent catheterization or indwelling catheter
Community-dwelling
Disqualifiers
Psychiatric or psychologic conditions impacting ability to consent
Trial population
Participants will be recruited from populations that have used Lactobacillus, gentamicin, or combination of the two.
Trial design
Other
Other
Treatments tested in this trial
Not listed
Trial groups
Trial outcomes
Primary outcomes
Advancing intravesical instillation for urinary health
Qualitative interviews will be coded, and themes how to advance intravesical instillation for urinary health will emerge.
Sponsors and contacts
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Medstar Health Research Institute
Lead sponsor
Congressionally Directed Medical Research Programs
Collaborator