To construct a prediction model of progesterone sensitivity in patients with endometrial cancer treated with fertility preservation
Have a confirmed pathological diagnosis based upon hysteroscopy: atypical endometrial hyperplasia or histologically prove well-differentiated EEC G1 without myometrial invasion
No signs of suspicious extrauterine involvement on enhanced magnetic resonance imaging (MRI) or enhanced computed tomography (CT) or ultrasound
Have a desire for remaining reproductive function or uterus
Good compliance with adjunctive treatment and follow-up
Acute liver disease or liver tumor (benign or malignant) or renal dysfunction
Pregnancy or potential pregnancy
Confirmed diagnosis of any cancer in reproductive system
Acute severe disease such as stroke or heart infarction or a history of thrombosis disease
This study focused on young, pre-menopausal patients with atypical endometrial hyperplasia or endometrioid adenocarcinoma diagnosed by hysteroscopic biopsy, who had a strong desire to preserve reproductive function.
Other
Other
No intervention
Other interventionNo intervention
sensitivity
The sensitivity of the prediction model
accuracy
The accuracy of the prediction model
false-negative rate
The false-negative rate of the prediction model
false-positive rate
The false-positive rate of the prediction model
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Peking University People's Hospital
Lead sponsor
Peking University
Collaborator
Beihang University
Collaborator
