PCOS and Brain Health
ConditionPCOS
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexFemale
Age18-45
SponsorUniversity of Wisconsin, Madison
About this trial
The purpose of this study is to determine how polycystic ovary syndrome (PCOS) impacts overall brain health, such as cerebral blood flow (CBF), brain structure and connectivity, and cognitive performance. 45 reproductive aged (18-45 years) individuals with ovaries, with and without PCOS, will be enrolled to complete brain structure and CBF scans via magnetic resonance imaging (MRI) over 2 testing visits and can expect to be on study for approximately 5 hours over a 1 to 3 month period.
Eligibility criteria
Qualifiers
Presence of clinical hyperandrogenism or biochemical hyperandrogenism
A history of irregular menstrual cycles
Presence of polycystic ovarian morphology on ultrasound
Regular menstrual cycles (not meeting criteria for irregular cycles above)
Disqualifiers
Current pregnancy
Preexisting diagnosis of type 1 diabetes
Severe obesity (body mass index (BMI) greater than 45kg/m2)
Preexisting diagnosis of hypertension requiring antihypertensive medication or blood pressure of greater than 160/100 on two separate occasions during clinical care
Trial design
Treatments tested in this trial
- MRI Visit
- Laboratory Visit
Treatment groups
45 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov