About this trial
This study aims to evaluate the clinical value of point-of-care multiplex PCR testing (POCT) in guiding early diagnosis and target treatment for acute respiratory infections in primary healthcare settings.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Onset time<=7 days;
First visit;
Age>=18 years old;
Patients with acute upper respiratory tract infection with severe high-risk factors, or patients with acute lower respiratory tract infection;
Disqualifiers
The doctor judges that the disease is serious and requires hospitalization;
New unclear consciousness;
Respiratory rate>=30 beats/min;
Hypoxemia or respiratory failure;
Trial design
Parallel
Treatments tested in this trial
point-of-care multiplex PCR test
Diagnostic testcommunity health care center in intervention group were provided with point-of-care multiplex PCR test (POCT) plus routine test. POCT testing was recommended for all enrolled patients presenting with acute respiratory infections who meet the predefined inclusion criteria. The therapeutic interventions were determined by health-care workers on the basis of POCT result, clinical assessment and guideline.
Treatment groups
Trial outcomes
Primary outcomes
The incidence rates of respiratory failure and hospitalization
Secondary outcomes
Proportion of patients receiving an immediate antiviral treatment
Proportion of patients receiving an immediate antiviral treatment by age, sex comorbidities, Immune status, season
Proportion of patients receiving antiviral treatment
Proportion of patients receiving antibiotic treatment
Sponsors and contacts
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