The purpose of this study is to evaluate whether an intervention called Pediatric Medication Therapy Management (pMTM) improves the identification and management of medication-related problems among children with medical complexity and polypharmacy.
2-18 years old
≥1 complex chronic condition (CCC)
≥5 current medications (including prescription, as needed, and over-the-counter medications)
Receives primary care at Children's Hospital Colorado
Non-English speaking
Sibling or family member already enrolled in this study
Parallel
Pediatric Medication Therapy Management (pMTM)
Other interventionThe pMTM intervention is comprised of 3 activities: comprehensive review of the medication regimen; optimization of the medication regimen; and creation of the medication action plan.
Medication-Related Problem (MRP) Count
A MRP is a clearly defined event involving medication therapy that interferes with an optimum outcome for a specific patient, including: inappropriate or unnecessary therapy; suboptimal therapy; undertreated symptom; adverse drug event; major drug-drug interaction; duplication of therapy; or, unclear prescription instruction.
Change in Parent-Reported Outcomes of Symptoms (PRO-Sx) Global Symptom Score
The PRO-Sx instrument assesses 28 physical and psychological symptoms over the past week. The study instrument is designed to be completed by a full-proxy parent and contains 28 symptom items, each with 4-point scores for domains of frequency, severity, and extent of bother. Based on these components, a global symptom score and individual symptom scores can be calculated (0-100 scale, with 100 being the worst). Change equals the 90-day score minus the baseline score.
Acute Healthcare Visit Count
Unplanned acute healthcare visits include: ambulatory sick visits; emergency room visits; and, inpatient hospitalizations.
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University of Colorado, Denver
Lead sponsor
Agency for Healthcare Research and Quality (AHRQ)
Collaborator
