Health TrialsbyHealthPanel

Pediatric PET/MR Image Registry

ConditionsSoft TissueLymphomaOsteosarcoma
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
AgeUp to 40
SponsorStanford University

About this trial

The purpose of this study is to compare whole body magnetic resonance (MR) imaging, whole body positron emission tomography (PET)/MR imaging, and (if available) PET/Computed Tomography (CT) imaging for the diagnosis of tumors in children and young adults. Sensitivities, specificities and diagnostic accuracies of the different imaging modalities will be compared for significant differences.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Patients with proven solid tumors or newly diagnosed mass strongly suspected to represent a solid tumor.

We might also include some patients with leukemia if there is concern for a focal lesion in any of their organs.

Participant's parents (if participant is under 18) or the participant (if participant is 18 years or older) must willingly give written informed consent prior to any image transfer to the image registry.

Disqualifiers

Patient has contraindications for MRI or PET/MR. This includes patients with cardiac pacemakers or intracranial vascular clips as well as patients with a blood glucose level > 200 mg/dl.

Lack of parental permission (if participant is younger than 18) or lack of informed consent (if participant is at least 18 years of age).

Patient has a CNS primary tumor.

Pregnant women and fetuses

Trial population

Pediatric and young adult (\<40 years) male or female subjects with proven solid tumors or newly diagnosed mass strongly suspected to represent a solid tumor

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

  • PET/MR imaging

    Diagnostic test

    undergo PET/MR imaging

  • MR imaging

    Diagnostic test

    Undergo MR imaging

  • PET/CT imaging

    Diagnostic test

    Undergo PET/CT imaging

Treatment groups

100 Participants
are divided into 1 treatment group
Group A: Image Registry3 interventions

Trial outcomes

Primary outcomes

1

Number of tumors

Number of tumors detected on whole body MRI, PET/MR and (if available) PET/CT scans.

Time frame
up to 12 months

Secondary outcomes

1

Metabolic activity of tumors

Metabolic activity of tumors determined by Standardized Uptake Values (SUV) on PET/MR and (if available) PET/CT scans.

Time frame
up to 12 months

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Stanford University

Lead sponsor

National Cancer Institute (NCI)

Collaborator

Source ClinicalTrials.gov
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