People Bereaved by Violent Death : Negative Event Biases and Temporal Perception
ConditionPost Traumatic Stress Disorder
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-65
SponsorHôpital le Vinatier
About this trial
A violent death is defined by its brutality, unexpectedness and is secondary to an external cause (suicide, homicide, accident). Bereavement following a violent death constitutes a particular clinical situation, at risk of complications. Research on bereavement after a violent death shows higher risks of psychiatric and somatic complications than in bereavement by non-violent death. These complications, sometimes comorbid, take the form of depressive episodes, post-traumatic stress disorders, suicidal behavior and prolonged grief disorders after 12 months, precociously mediated by ruminations.
Processes responsible for this increased risk of complications are poorly documented. Current literature relates mainly to socio-demographic and epidemiological factors which, alone, do not explain this difference in risks. Further research is needed exploring other kinds of data and processes. To our knowledge, there is no description of early neurocognitive functioning in people bereaved after violent death. This study aims at exploring early neurocognitive processes which can lead to complications in people bereaved by violent death.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
An age between 18 and 65 years old
Recent bereavement by violent death of a relative in first and second degree
Disqualifiers
Protected adults
Lack of mastering French language
History of neurodegenerative disorder
History of psychiatric disorder treated pharmacologically with modification of the basic treatment in the month preceding the death
Trial design
Design model
Parallel
Treatments tested in this trial
Diagnosis of depressive episode or post traumatic stress disorder
Other interventionClinical diagnosis of depressive episode or post traumatic stress disorder, confirmed
No diagnosis of depressive episode or post traumatic stress disorder
Other interventionNo elements in clinical assessment for the diagnosis of a depressive episode or post traumatic stress disorder
Treatment groups
61 Participants
are divided into 2 treatment groupsGroup A: Group with complications at 3 monthOther 1 intervention
Group B: Group without complication at 3 monthOther 1 intervention
Trial outcomes
Primary outcomes
1
Amplitude of the Late Positive Potential (LPP) component in unpredictable event condition
Measure in Electroencephalography (EEG) of the Late Positive Potential (LPP), an Event Related Potential (ERP) relating to attention biases
Time frame
Between Day15 and Day30 after the death of one's loved oneSecondary outcomes
1
Amplitude of the Contingent Negative Variation (CNV ) component in unpredictable event condition
Measure in Electroencephalography (EEG) of the Contingent Negative Variation (CNV), EEG measures relating to temporal perception
Time frame
Between Day15 and Day30 after the death of one's loved one2
Amplitude of the alpha and beta power in unpredictable event condition
Measure in Electroencephalography (EEG) of the alpha and beta power, EEG measures relating to temporal perception
Time frame
Between Day15 and Day30 after the death of one's loved one3
Comparison of Constant Errors (CE) relative to time estimates in the unpredictability condition (D15-J30) in people developing a psychiatric complication at 3 months and in people not developing these complications.
Proportion of overestimation of the duration preceding an unpredictable event, and calculation of the point of subjective equality, for measurements of constant errors (CEs) corresponding to the difference between the effective time and the point of subjective equality for each subject
Time frame
Between Day15 and Day30 after the death of one's loved oneSponsors and contacts
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Source ClinicalTrials.gov