Performance of 18F-FDG Micro-PET-CT in the Assessment of Surgical Margins in Head and Neck Cancer

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorCentre Henri Becquerel

About this trial

The purpose of this study is to evaluate the diagnostic performance of 18F-FDG micro-PET-CT in malignant Head and neck cancer compared to definitive histological analysis (gold standard).

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Signed informed consent

Adult, male or female, aged 18 or over

Patient with a malignant tumor of the oral cavity, oropharynx, hypopharynx, larynx, sinuses, or salivary glands, regardless of lymph node status (any N) M0, operable

Member or beneficiary of a social security plan

Disqualifiers

Child-Pugh C liver failure

Patients under guardianship, conservatorship, or legal protection

Patients deprived of their liberty

Pregnant or breastfeeding women

Trial design

Design model

Single group

Treatments tested in this trial

  • micro PET/CT

    Device

    PET/T of the speciment after surgery

Treatment groups

10 Participants
are divided into 1 treatment group
Group A: ExperimentalExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Evaluate the diagnostic performance of 18F-FDG micro-PET-CT in malignant ENT tumors compared to definitive histological analysis (gold standard).

Estimate the performance of micro-FDG PET in defining surgical margins and compare with histology by measuring the number of quadrants affected by each technique on the surgical specimen

Time frame
Surgery

Secondary outcomes

Other outcomes

Sponsors and contacts

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