Perfusion Index and Spinal Hypotension in Day-Case Knee Arthroscopy

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-65
SponsorAnkara Etlik City Hospital

About this trial

This prospective observational study aims to investigate the role of the baseline perfusion index (PI) in predicting spinal anesthesia-induced hypotension (SAIH) in ASA I-II patients undergoing day-case knee arthroscopy.

Spinal anesthesia is a widely preferred technique for lower extremity surgeries, including knee arthroscopy. However, sympathetic blockade during spinal anesthesia frequently leads to significant hemodynamic instability, particularly hypotension, which can result in adverse perioperative outcomes. While age and baseline blood pressure are traditional risk factors, they often fail to accurately predict the onset of hypotension in healthy populations. The perfusion index (PI), a non-invasive parameter measured via pulse oximetry, reflects peripheral vascular tone and baseline sympathetic activity. An elevated baseline PI indicates baseline vasodilation and a higher susceptibility to sympathectomy, potentially offering an early and non-invasive prediction of SAIH before the hemodynamic collapse occurs.

The primary outcome of the study is the incidence of spinal anesthesia-induced hypotension (defined as a mean arterial pressure \< 65 mmHg or a decrease in systolic blood pressure \> 25% from baseline). Secondary outcomes include the onset time of sensory block, and intraoperative ephedrine and fluid requirements.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Between the ages of 18-65

Having an ASA Score of I-II

Including data collection of parts that underwent knee arthroscopy

Disqualifiers

Patients under 18 and over 65 years of age

Patients with ASA Score III and above

Trial population

Adult patients with American Society of Anesthesiologists physical status I or II who are scheduled for elective knee arthroscopy under spinal anesthesia at Etlik City Hospital will be consecutively screened for participation.

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

No trial groups listed

Trial outcomes

Primary outcomes

1

Spinal anesthesia-induced hypotension

Defined as a mean arterial pressure \< 65 mmHg or a decrease in systolic blood pressure \> 25% from baseline

Time frame
During the surgery

Secondary outcomes

1

Investigation of Sensory Block Kinetics

Time to reach the T10 sensory dermatome

Time frame
Periprocedural
2

Vasopressor Consumption

Total amount of rescue vasopressor (Ephedrine) consumed to treat hypotension during the intraoperative period

Time frame
During the surgery

Other outcomes

Sponsors and contacts

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