About this trial
This prospective observational study aims to investigate the role of the baseline perfusion index (PI) in predicting spinal anesthesia-induced hypotension (SAIH) in ASA I-II patients undergoing day-case knee arthroscopy.
Spinal anesthesia is a widely preferred technique for lower extremity surgeries, including knee arthroscopy. However, sympathetic blockade during spinal anesthesia frequently leads to significant hemodynamic instability, particularly hypotension, which can result in adverse perioperative outcomes. While age and baseline blood pressure are traditional risk factors, they often fail to accurately predict the onset of hypotension in healthy populations. The perfusion index (PI), a non-invasive parameter measured via pulse oximetry, reflects peripheral vascular tone and baseline sympathetic activity. An elevated baseline PI indicates baseline vasodilation and a higher susceptibility to sympathectomy, potentially offering an early and non-invasive prediction of SAIH before the hemodynamic collapse occurs.
The primary outcome of the study is the incidence of spinal anesthesia-induced hypotension (defined as a mean arterial pressure \< 65 mmHg or a decrease in systolic blood pressure \> 25% from baseline). Secondary outcomes include the onset time of sensory block, and intraoperative ephedrine and fluid requirements.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Between the ages of 18-65
Having an ASA Score of I-II
Including data collection of parts that underwent knee arthroscopy
Disqualifiers
Patients under 18 and over 65 years of age
Patients with ASA Score III and above
Trial population
Adult patients with American Society of Anesthesiologists physical status I or II who are scheduled for elective knee arthroscopy under spinal anesthesia at Etlik City Hospital will be consecutively screened for participation.
Trial design
Cohort
Prospective
Treatments tested in this trial
Not listed
Trial groups
Trial outcomes
Primary outcomes
Spinal anesthesia-induced hypotension
Defined as a mean arterial pressure \< 65 mmHg or a decrease in systolic blood pressure \> 25% from baseline
Secondary outcomes
Investigation of Sensory Block Kinetics
Time to reach the T10 sensory dermatome
Vasopressor Consumption
Total amount of rescue vasopressor (Ephedrine) consumed to treat hypotension during the intraoperative period
Sponsors and contacts
Click on the lead sponsor to view all of their trials.