About this trial
This study aims to evaluate changes in perfusion index (PI) in pediatric patients undergoing elective surgery under low-flow anesthesia. PI will be monitored at multiple intraoperative and postoperative time points to assess its relationship with hemodynamic stability and depth of anesthesia. The study will also investigate whether low-flow anesthesia affects the incidence of emergence agitation (EA). Patients will be assigned to either low-flow or normal-flow anesthesia groups based on routine clinical practice. No intervention will be applied beyond standard care. The findings are expected to provide insight into the predictive value of PI in postoperative recovery and support safer anesthesia practices in pediatric populations.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
ASA I-II pediatric patients
Age 2 to 12 years
Undergoing elective surgery lasting between 1-6 hours
Informed consent obtained from parents/guardians
Disqualifiers
Cardiovascular, respiratory, neurological, metabolic, or endocrine disorders
Premature birth with corrected age < 2 years
Obesity or severe malnutrition (BMI <5th or >95th percentile)
Psychiatric or neurodevelopmental disorders (e.g., autism)
Trial design
Parallel
Treatments tested in this trial
Low-Flow Anesthesia (LFA)
Procedure/SurgeryGeneral anesthesia with a fresh gas flow rate of 1 L/min (50% oxygen + 50% air).
Treatment groups
Trial outcomes
Primary outcomes
Change in Perfusion Index (PI)
Perfusion Index (PI) will be measured at 11 predefined perioperative time points to assess its intraoperative variation and its potential correlation with anesthesia depth and emergence profile in pediatric patients undergoing low-flow vs normal-flow anesthesia.
Sponsors and contacts
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