Perinatal Thymic DYsregulation: Characterization of Perinatal Mood Episodes

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age18+
SponsorCentre Hospitalier Charles Perrens, Bordeaux

About this trial

The perinatal period is recognized as a time of heightened psychological vulnerability. This research aims to improve the diagnosis and therapeutic management of mood episodes occurring during this time. It is integrated into routine clinical care and seeks to standardize the evaluation of criteria used to characterize mood episodes, while also exploring relevant contextual factors.

Traditionally, clinical attention has focused on postnatal depression; however, increasing evidence highlights the presence of hypomanic symptoms-such as distractibility, reduced need for sleep, tachypsychia, and irritability-during the postpartum period. These symptoms may coexist with depressive features, resulting in complex clinical presentations that are often difficult to recognize and manage. Consequently, many cases go undiagnosed and untreated.

Current research has largely concentrated on depressive episodes (perinatal depression), with less emphasis on manic, hypomanic, or mixed episodes indicative of bipolar disorder. A systematic evaluation of hypomanic symptoms occurring alongside depressive symptoms in the postpartum period could refine clinical diagnosis and support more targeted and effective therapeutic interventions.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Women over 18 years old

Pregnant or having given birth less than a year ago

First psychiatric consultation for the pregnancy concerned.

Good command of the French language.

Disqualifiers

Women who gave birth more than a year ago.

Participant under psychiatric care

Participant under court protection

Trial design

Design model

Single group

Treatments tested in this trial

  • self-questionnaires

    Other intervention

    Patients who volunteer to take part in the research will complete self-questionnaires before their appointment with the psychiatrist.

Treatment groups

200 Participants
are divided into 1 treatment group
Group A: Usual careExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Detailed description of the Edinburg Postnatal (EPDS) scale

A sensitivity analysis will be carried out on the group of patients with an EPDS score greater than 12, and a comparison between these patients and patients with an EPDS score equal to or less than 12 will also be carried out

Time frame
1 day
2

Detailed description of Multidimensional Assessment of Thymic (MAThyS) scale

Time frame
1 day

Secondary outcomes

1

Association of the risk factors Perceived Stress Scale (PSS) will be assessed by self-report

the level of perceived stress by self report score\>=14 characterize a high level of perceived stress

Time frame
1 day
2

Association of the risk factors Medical Outcomes Study -Social Support Survey (MOS-SSS) will be assessed by self-report

the level of perceived social support by self-report scale scores can range from 19 to 95, with a median score of 57

Time frame
1
3

Association of the risk factors Perceived Professional Social Support (QSSP-P) will be assessed by self-report

the level of perceived social support in the professional by self-report. scale scores pcan range from 12 to 120, with a median score of 66

Time frame
1

Other outcomes

Sponsors and contacts

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