Patient undergoing surgery is exposed to many stressors: diachronic (gesture anticipation), synchronic (intraoperative aggression) and historical (subject's personality). Reducing the level of stress experienced is a factor for improving the quality of the surgical gesture and the simplicity of the follow-up. The previous methods used were intended to reduce the body's reactivity to aggressions through anaesthesia consultation and L-Tyrosine supplementation. Currently with the progression of outpatient surgery and the need for early rehabilitation, L-Tyrosine supplementation is suppressed to improve recovery. Some patients, however, have a high level of stress that may require anxiolysis when the ideal treatment does not exist (ineffective hydroxyzine, benzodiazepines having many side effects). The strategy of this work is to improve the body's ability to respond to stressors, by administering l-tyrosine with no impact on waking or returning home.
Membership of a social security scheme or equivalent
At least 18 years of age
Able to express consent
Indication of unilateral or bilateral inguinal hernia cure
Surgical indication for another reason or hernial cure associated with another procedure
Smoking estimated at more than 35 pack-years
History of psychiatric pathology
ASA 3 or 4 according to the American Society of Anesthesiologists classification. As a reminder, an ASA 3 class concerns a patient with a severe but not disabling general disease, and an ASA 4 class concerns a patient with a disabling general disease involving the vital prognosis.
Parallel
L-tyrosine supplementation
Dietary supplementL-Tyrosine supplementation before surgery for inguinal hernia under general anaesthesia
Placebo supplementation
Dietary supplementPlacebo supplementation before surgery for inguinal hernia under general anaesthesia
Variation of anxiety status
Anxiety score measured using Y-A STAI
Other stress markers variation
anxiety visual analogue scale (from 0 to 10, 10 is worst)
Other stress markers variation
anxiety visual analogue scale (from 0 to 10, 10 is worst)
Other stress markers variation
heart blood pressure (Systolic and diastolic)
Other stress markers variation
heart blood pressure (Systolic and diastolic)
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