About this trial
In patients achieving clinical remission following a flare, artificial intelligence can reliably predict a new flare within the next 12 months utilizing clinical and objective information at day 0 and week 8.
Secondary endpoints:
* An artificial intelligence model's precision in predicting a new flare within 2 and 3 years * An artificial intelligence model's precision to rule out patients who will not experience a new flare within 1, 2 and 3 year
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Signed informed consent
Diagnosis of UC for at least 1 year
Relapse due to UC.
First endoscopic and histological evaluation of the flare
Disqualifiers
Well-founded doubt that the flare is due to other than the patients UC
Trial population
This is a prospective cohort of a total of 400 UC patients with an active flare
Trial design
Cohort
Prospective
Treatments tested in this trial
Deep learning model
Other interventionUse of deep learning model to predict individual patients disease course
Treatment groups
Trial outcomes
Primary outcomes
Flare I
Evaluate the accuracy in predicting a flare within 1 year after the patient's initial flare using machine learning methods.
Secondary outcomes
Flare II
Evaluate the accuracy in predicting a flare within 2 years, after the patient's initial flare, using machine learning methods.
Flare III
Evaluate the accuracy in predicting a flare within 3 years, after the patient's initial flare, using machine learning methods.
Sponsors and contacts
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