A new analytical method for determining beta-lactam antibiotic concentrations in the blood of intensive care patients is to be evaluated. Patients receive antibiotic therapy with beta-lactam antibiotics in the general surgery intensive care unit. Blood samples are collected daily for routine clinical testing; a portion of these samples is used for the new method. The antibiotic levels, routinely measured using the gold standard, are documented and used as a reference point. The goal of the study is to establish a rapid and cost-effective method for determining beta-lactam antibiotic levels, which will subsequently enable rapid dose adjustment.
Valid informed consent form (prospective, retrospective, or provided by a legal representative)
Antibiotic therapy with a beta-lactam antibiotic in the intensive care unit or intermediate care unit of the Department of General Surgery at UMG
Patients without a valid informed consent form
Patents that are treated with beta-lactam antibiotics in the ICU or IMC unit of the Department of General Surgery at UMG
Case-only
Prospective
Not listed
Blood levels of beta-lactam antibiotics
Blood levels of beta-lactam antibiotics are measured both through routine clinical testing and using the newly developed analytical method. Blood samples are collected once a day for this purpose. Changes in blood levels are monitored over several days.
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Dr. T. Perl
Lead sponsor
University of Göttingen
Sponsor institution
This trial is not recruiting at the moment. You can still explore other options:
