About this trial
This study will assess the long-lasting effects of personalized theta burst stimulation (TBS), a repetitive form of transcranial magnetic stimulation (TMS), over the left prefrontal cortex on the approach/avoidance behavior. TBS will be personalized based on the prefrontal theta rhythm captured with electroencephalography (EEG). The main questions it aims to answer are: 1. does a single session of personalized TBS synchronized with the individual theta rhythm over the left prefrontal cortex results in the outlasting changes in the individual behavior? 2. Does TBS results in the brain rhythms' changes as measured using resting-state EEG?
Eligibility criteria
Qualifiers
Participants must be legal adults between the ages of 18 to 65;
Able and willing to complete study procedures and tasks.
Disqualifiers
History or evidence of chronic neurological or mental disorder;
Chronic condition that requires pharmacological treatment over the course of study participation;
Pregnancy or breastfeeding;
History or evidence of alcohol or drug addiction;
Trial design
Treatments tested in this trial
- TBS-EEG
- TBS-EEG / Spatial Control
- TBS / Temporal Control
- TBS-EEG / Dose Control
Treatment groups
Sponsors and collaborators
Northwestern University
Lead sponsor
National Institute of Mental Health (NIMH)
Collaborator