About this trial
This study aims to evaluate the pharmacokinetic interactions between HUC2-744-A and HUC2-744-B following monotherapy or co-administration under multiple-dose conditions.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Healthy adults
Subjects with a body weight of 50 kg or more and a BMI within the range of 18.0 to 29.9 kg/m²
Disqualifiers
History or presence of clinically significant cardiovascular, respiratory, hepatic, renal, hematologic, gastrointestinal, endocrine, immunologic, dermatologic, neurological, or psychiatric disease
Presence of acute disease symptoms within 28 days prior to the first dosing
History of any disease that may affect drug absorption, distribution, metabolism, or excretion
Hypersensitivity or history of clinically significant hypersensitivity to atorvastatin, telmisartan, drugs containing ingredients of the same class, or other medications (e.g., aspirin, antibiotics, dihydropyridine derivatives)
Trial design
Single group
Treatments tested in this trial
Atorvastatin Calcium
DrugHUC2-744-A
Telmisartan
DrugHUC2-744-B
Treatment groups
Trial outcomes
Primary outcomes
AUCτ
Area Under the Curve of telmisartan, atorvastatin
Cmax,ss
Maximum concentration at steady state of telmisartan, atorvastatin
Secondary outcomes
Cmax,ss
Maximum concentration at steady state of 2-hydroxy atorvastatin
AUCτ
Area Under the Curve of 2-hydroxy atorvastatin
Sponsors and contacts
Click on the lead sponsor to view all of their trials.
This trial is not recruiting at the moment. You can still explore other options: