A Double-Blinded Study on Rapid and Sustained Pain Relief Topical Cannabidiol for Plantar Fasciitis

Trial statusNot yet recruiting
Trial phasePhase 1
Trial typeInterventional
Biological sexAll
Age18-85
SponsorUniversity of Florida

About this trial

This prospective, double-blinded, placebo-controlled study evaluates the efficacy of a 6000 mg transdermal CBD cream in adults with plantar fasciitis. Fifty participants will apply either CBD or placebo once daily for one month.

Eligibility criteria

Qualifiers

Patients aged 18-85

Clinical diagnosis of plantar fasciitis by a qualified provider

Symptomatic for at least four weeks with plantar heel pain consistent with plantar fascia involvement

Baseline average pain score that meets eligibility threshold as defined in the protocol (?)

Disqualifiers

Special populations and consent limitations. Pregnancy, breastfeeding, prisoners, inability to provide informed consent, or inability to complete study procedures

Contraindications to topical products or CBD. History of allergy or sensitivity to cannabinoids, excipients, or topical creams used in the study

Confounding dermatologic conditions at the application site. Open wounds, active infection, dermatitis, ulceration, or recent burns on the heel or midfoot

Recent or planned procedures that alter outcomes. Corticosteroid injection, platelet rich plasma, surgery, immobilization, or shockwave therapy within the protocol washout window

Trial design

Treatments tested in this trial

  • transdermal CBD cream (Tolcylen®, Marlinz Pharma)
  • Matched Placebos

Treatment groups

50 Participants
are divided into 2 treatment groups

Sponsors and collaborators