About this trial
The aim of this study is to assess the pharmacokinetics, safety and tolerability of single-dose Adagrasib (BMS-986503) in healthy participants of Japanese descent
Eligibility criteria
Qualifiers
Participants must be of Japanese descent (both biological parents of the participant are ethnically Japanese).
Participants must be healthy adult without clinically significant deviation from normal in medical history, PE, 12-lead ECG, vital sign measurements, and clinical laboratory assessments as determined by the investigator.
Participants must have Body mass index of 18.0 kg/m2 to 32.0 kg/m2.
Participants must have Total body weight ≥ 50 kg.
Disqualifiers
Participants must not have significant history or clinical manifestation of any metabolic, allergic, dermatological, renal, hematological, pulmonary, cardiovascular, gastrointestinal, neurological, respiratory, endocrine, or psychiatric disorder, as determined by the investigator.
Other protocol defined Inclusion/Exclusion criteria apply.
Trial design
Treatments tested in this trial
- Adagrasib