Analgesic Efficacy of Pre-Operative Dose of Palmitoylethanolamide in Patients Undergoing Total Knee Arthroplasty

ConditionTotal Knee Replacement

Trial statusNot yet recruiting

Trial phasePhase 1, Phase 2

Trial typeInterventional

Biological sexAll

Age40-80

SponsorAbdelrahman Gaber Sayed Elkhateeb

About this trial

Analgesic Efficacy of Pre-Operative Dose of palmitoylethanolamide in Patients Undergoing total Knee Arthroplasty, A Randomized Double-Blinded Controlled Trial.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

None

Disqualifiers

Rheumatoid Arthritis

History of Renal impairment

Any complications of surgery as( iatrogenic fractures -patient with low bone quality that needs long stem prosthesis -patient with depressed tibial plateau that needs graft )

Patients refused to be enrolled in the study

Trial design

Design model

Parallel

Treatments tested in this trial

Effect of two different drugs on post operative pain after TKA
Drug
Effect of preoperative dose of palmetoyelethenolamide in post-op pain in patient undergoing Total Knee Replacement

Treatment groups

1 Participants

are divided into 2 treatment groups

Group A: Placebo effect on post operative pain after TKAExperimental treatment 1 intervention

Group B: Palmetoyelethenolamide effect on post operative pain after TKAExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

Decrease post operative pain

Visual Analog Scale (VAS) will be used at 6, 12, 24 hours post-surgery for assessment of Pain. Scale from one to ten Ten means patient in sever pain One means patient is well The higher the score the pain is severer

Time frame

Frist 24 hours postoperative

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Abdelrahman Gaber Sayed Elkhateeb

Lead sponsor

Assiut University

Sponsor institution

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: